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Lawrence C Sowers Selected Research

5-Methylcytosine (5 Methylcytosine)

1/2022Measurement of deaminated cytosine adducts in DNA using a novel hybrid thymine DNA glycosylase.
1/2017How does inflammation drive mutagenesis in colorectal cancer?
6/2007Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancers.
2/2007Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.

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Lawrence C Sowers Research Topics

Disease

12Inflammation (Inflammations)
11/2017 - 09/2004
11Neoplasms (Cancer)
06/2022 - 01/2005
2Glioblastoma (Glioblastoma Multiforme)
06/2022 - 11/2017
2Pulmonary Hypertension
02/2012 - 02/2011
2Brain Injuries (Brain Injury)
09/2007 - 06/2005
1Aneuploidy (Aneuploid)
06/2022
1COVID-19
12/2020
1Traumatic Brain Injuries (Traumatic Brain Injury)
01/2018
1Neuroblastoma
01/2018
1Mitochondrial Diseases (Mitochondrial Disease)
01/2018
1Necrosis
01/2018
1Hypoxia (Hypoxemia)
11/2017
1Rett Syndrome (Rett's Disorder)
05/2017
1Nervous System Diseases (Neurological Disorders)
05/2017
1Burns
10/2016
1Opportunistic Infections (Opportunistic Infection)
10/2016
1Breast Neoplasms (Breast Cancer)
05/2015
1Glioma (Gliomas)
01/2014
1Hemolysis
02/2011
1Brain Edema (Cerebral Edema)
11/2008
1Osteosarcoma (Osteogenic Sarcoma)
12/2007
1Reperfusion Injury
05/2007
1Ischemia
05/2007
1Pain (Aches)
06/2005
1Asphyxia (Suffocation)
06/2005
1Genomic Instability
12/2002

Drug/Important Bio-Agent (IBA)

8DNA (Deoxyribonucleic Acid)IBA
01/2017 - 09/2004
5CytosineIBA
01/2022 - 01/2005
45-Methylcytosine (5 Methylcytosine)IBA
01/2022 - 02/2007
45-chlorocytosineIBA
11/2013 - 02/2007
35-chlorouracilIBA
04/2010 - 06/2008
3Hypochlorous Acid (Hypochlorite)IBA
04/2010 - 06/2008
2EnzymesIBA
11/2017 - 12/2002
2Arginine (L-Arginine)FDA Link
11/2017 - 01/2014
2Carrier Proteins (Binding Protein)IBA
05/2017 - 06/2007
2NitritesIBA
02/2012 - 02/2011
2Biological ProductsIBA
04/2010 - 12/2009
2Peroxidase (Myeloperoxidase)IBA
11/2008 - 09/2004
1Methionine (L-Methionine)FDA Link
06/2022
1DNA Glycosylases (DNA Glycosylase)IBA
01/2022
1Antiviral Agents (Antivirals)IBA
12/2020
1Rifampin (Rifampicin)FDA LinkGeneric
01/2018
13- (4,5- dimethyl- 2- thiazolyl)- 2,5- diphenyl- 2H- tetrazolium bromideIBA
01/2018
1Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2018
1Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
11/2017
1CarbonIBA
11/2017
1Histones (Histone)IBA
11/2017
1IsotopesIBA
11/2017
1Peptides (Polypeptides)IBA
11/2017
1Proteins (Proteins, Gene)FDA Link
11/2017
1Pyruvic Acid (Pyruvate)IBA
11/2017
1Lactic Acid (Lactate)FDA LinkGeneric
11/2017
1ProteomeIBA
11/2017
1Biomarkers (Surrogate Marker)IBA
01/2017
1OligodeoxyribonucleotidesIBA
10/2016
1CytoglobinIBA
05/2015
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
05/2015
1Phosphotransferases (Kinase)IBA
05/2015
1Reactive Oxygen Species (Oxygen Radicals)IBA
05/2015
1LigandsIBA
05/2015
1p38 Mitogen-Activated Protein KinasesIBA
05/2015
1JNK Mitogen-Activated Protein KinasesIBA
05/2015
12- (4- amino- 3- methylphenyl)- 5- fluorobenzothiazoleIBA
05/2015
1Amino AcidsFDA Link
01/2014
1Glutamic Acid (Glutamate)FDA Link
01/2014
1Tryptophan (L-Tryptophan)FDA Link
01/2014
1S-nitrosohemoglobinIBA
02/2012
1NitratesIBA
02/2012
1Nitric Oxide (Nitrogen Monoxide)FDA Link
02/2012
1Pharmaceutical PreparationsIBA
04/2011
1AerosolsIBA
02/2011
1Hemoglobins (Hemoglobin)IBA
02/2011
1Nucleic AcidsIBA
12/2009
1OligonucleotidesIBA
08/2009
13-nitrotyrosineIBA
11/2008
15-hydroxyuracilIBA
06/2008
15-hydroxycytosineIBA
06/2008
1acetovanillone (apocynin)IBA
09/2007
1Ethanol (Ethyl Alcohol)IBA
09/2007
1Protein Kinases (Protein Kinase)IBA
05/2007
1Analgesics (Analgesic Drugs)IBA
06/2005
1Opioid Analgesics (Opioids)IBA
06/2005
1ChlorineIBA
09/2004

Therapy/Procedure

2Therapeutics
01/2018 - 02/2012
1Drug Therapy (Chemotherapy)
11/2017
1Aftercare (After-Treatment)
10/2016